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KMID : 1161420110140090907
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Journal of Medicinal Food
2011 Volume.14 No. 9 p.907 ~ p.911
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Antimicrobial Properties of Green Tea Extract Against Cariogenic Microflora: An In Vivo Study
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Ferrazzano Gianmaria F.
Roberto Lia
Amato Ivana
Cantile Tiziana
Sangianantoni Giancarla
Ingenito Aniello
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Abstract
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The aim of the present study was to test in vivo the effectiveness of an experimental green tea extract in reducing levels of mutans streptococci and lactobacilli in saliva by means of selective culture medium. Sixty-six healthy patients ranging in age from 12 to 18 years were recruited and randomly divided into two groups: Group A (n=33) and group B (n=33). Group A subjects were asked to rinse their mouths with 40?mL of an experimental green tea extract, for 1 minute, three times a day for a week, whereas Group B subjects were asked to rinse with 40?mL of a placebo mouth rinse. Saliva samples were obtained at baseline, 4 days, and 7 days. The counts of mutans streptococci and lactobacilli were investigated by chair-side kits. Data were statistically processed. A regression binary logistic analysis was done. The statistical significance level was established at P<.05. The experimental group showed a statistically significant reduction in colony counts of mutans streptococci and lactobacilli relative to the control group. These findings showed the efficacy of a green tea extract against cariogenic oral flora, opening a promising avenue of clinical applications in the preparation of specific and natural anticariogenic remedies.
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KEYWORD
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antimicrobial activity, cariogenic bacteria, green tea, polyphenol
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